Abstract

Volume.116 Number.2

Original article : Clinical science

Prevalence of Sleep-disordered Breathing in Patients with Retinal Vein Occlusion
Hidehito Kanai1, Tomoaki Shiba1, Yuichi Hori1, Yoshitsugu Saishin1, Takatoshi Maeno1, Mao Takahashi2
1 Department of Ophthalmology, Toho University Sakura Medical Center
2 Cardiovascular Centre, Toho University Sakura Medical Center

Purpose: To investigate the prevalence of sleep-disordered breathing (SDB) in retinal vein occlusion (RVO) patients.
Subject and method: Forty RVO patients who had undergone either vitreous surgery or anti-coagulation therapy were included in this study. Pulse oximetry was conducted during the night and 4% oxygen desaturation index (4% ODI times/hour) and mean SpO2 (%) were calculated. If 4% ODI≥5, SDB was diagnosed. The results were compared between branch retinal vein occlusion (BRVO), and central retinal vein occlusion (CRVO). In addition, simple linear regression analyses were conducted to investigate whether 4% ODI related to systemic factors for RVO patients, i.e., incidences of hypertension and diabetes and body mass index (BMI kg/m2).
Results: Forty two percent of the men, 33% of the women and 37% of all the RVO patients were diagnosed as having SDB. The prevalence of SDB and 4% ODI, and the mean SpO2 were not significantly different between the BRVO and CRVO cases. The incidences of diabetes tended to correlate to the 4% ODI, however, neither proved significant. The BMI had a statistic correlation with the 4% ODI.
Conclusion: The results of our study suggested that RVO cases have a high frequency of SDB. We believe that at the time of ophthalmic medical examinations or during the treatment of RVO, ophthalmologists should be aware of the possibility of SDB.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 116:81-85, 2012.

Key words
Retinal vein occlusion, Sleep-disordered breathing, Hypertension, Diabetes, Body mass index
Reprint requests to
Hidehito Kanai, M.D. Department of Ophthalmology, Toho University Sakura Medical Center. 564-1 Shimoshizu, Sakura-shi, Chiba-ken 285-8741, Japan