Abstract

Volume.116 Number.9

Original article : Clinical science

A Prospective Study of Postoperative Aqueous Flare in Trabeculectomy Alone Versus Phacotrabeculectomy
Masaru Inatani1,2, Minako Ogata-Iwao1, Yuji Takihara1, Keiichiro Iwao1,3, Toshihiro Inoue1, Nanako Kasaoka1, Hidenobu Tanihara1
1 Department of Ophthalmology and Visual Science, Kumamoto University Graduate School of Medical Sciences
2 Department of Ophthalmology, Faculty of Medical Science, University of Fukui
3 Department of Ophthalmology, Saga University Faculty of Medicine

Purpose: To compare trabeculectomy alone with phacotrabeculectomy in postoperative aqueous flare.
Subjects and Methods: Aqueous flare was prospectively measured using a laser flare-cell meter in open-angle glaucoma patients with cataract undergoing trabeculectomy with either mitomycin C or phacotrabeculectomy with mitomycin C. Flare was measured before surgery and at 2 and 4 weeks after surgery.
Results: Twenty-four patients who underwent trabeculectomy and 26 patients who underwent phacotrabeculectomy completed the study. There were no significant differences in flare values between the two groups at any point. Logistic regression analysis demonstrated that exfoliation glaucoma (odds ratio=8.978; p=0.0028) and postoperatively shallow anterior chamber (odds ratio=15.539; p=0.0074) were risk factors for high values of aqueous flare at 2 weeks after surgery.
Conclusions: Combined phacoemulsification does not enhance postoperative aqueous flare in trabeculectomy. Exfoliation glaucoma and postoperative shallow anterior chamber are factors in the elevation of aqueous flare.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 116: 856-861, 2012.

Key words
Primary open-angle glaucoma, Lens extraction, Blood-aqueous barrier, Intraocular lens
Reprint requests to
Masaru Inatani, M.D., Ph.D. Department of Ophthalmology, Faculty of Medical Science, University of Fukui. 23-3 Shimoaizuki, Matsuoka, Eiheiji, Yoshida-gun, Fukuiken 910-1193, Japan