Abstract

Volume.118 Number.10

Original article : Clinical science

Correlation of Intraocular Pressure Variation after Visual Field Examination with 24-hour Intraocular Pressure Variations in Primary Open-angle Glaucoma
Takahiko Noro1,2, Kenji Nakamoto3,4, Makoto Sato3,4, Noriko Yasuda5, Yoshinori Ito1, Shumpei Ogawa1, Tadashi Nakano1, Hiroshi Tsuneoka1
1 Department of Ophthalmology, The Jikei University School of Medicine
2 Department of Ophthalmology, Asao General Hospital
3 Department of Ophthalmology, Nippon Medical School
4 Department of Ophthalmology, Tokyo Metropolitan Police Hospital
5 Department of Ophthalmology, Showa University School of Medicine

Objectives: We retrospectively examined intraocular pressure variations after visual field examination in primary open angle glaucoma (POAG), together with its influencing factors and its association with 24-hour intraocular pressure variations.
Subjects and methods: Subjects were 94 eyes (52 POAG patients) subjected to measurements of 24-hour intraocular pressure and of changes in intraocular pressure after visual field examination using a Humphrey Visual Field Analyzer. Subjects were classified into three groups according to the magnitude of variation (large, intermediate and small), and 24-hour intraocular pressure variations were compared among the three groups. Factors influencing intraocular pressure variations after visual field examination and those associated with the large variation group were investigated.
Results: Average intraocular pressure variation after visual field examination was -0.28±1.90 (range -6.0∼+5.0) mmHg. No significant influencing factors were identified. The intraocular pressure at 3 a.m. was significantly higher in the large variation group than other two groups (p<0.001). Central corneal thickness was correlated with the large variation group (odds ratio=1.04; 95% confidence interval, 1.01-1.07; p=0.02).
Conclusion: No particular tendencies in intraocular pressure variations were found after visual field examination. Increases in intraocular pressure during the night might be associated with large intraocular pressure variations after visual field examination.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 118: 831-837, 2014.

Key words
Intraocular pressure (IOP), Visual field, 24-hour IOP variation, Primary open-angle glaucoma
Reprint requests to
Takahiko Noro, M. D. Department of Ophthalmology, The Jikei University School of Medicine. 3-25-8 Nishi-Shinbashi, Minato-ku, Tokyo 105-8461, Japan