Abstract

Volume.119 Number.10

Original article : Clinical science

Clinical Survey of Uveitis in Tokyo Medical and Dental University -Comparison between the Periods of 1998-2001 and 2007-2011
Masaru Miyanaga1,2, Hiroshi Takase1, Tatsushi Kawaguchi1, Koju Kamoi1, Kentaro Shimizu1, Mako Yokota1, Sunao Sugita3, Manabu Mochizuki1
1 Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU)
2 Department of Ophthalmology, Tokyo Metropolitan Hiroo Hospital
3 Laboratory for Retinal Regeneration, Center for Developmental Biology, RIKEN

Purpose: To investigate a clinical survey of uveitis in Tokyo Medical and Dental University Hospital.
Subjects and methods: The clinical records of patients with uveitis who were treated from October 1998 to December 2001 and from January 2007 to December 2011 were reviewed. The clinical results of both periods were compared.
Results: A total number of 455 patients (707 eyes) and 1091 patients (1716 eyes) were analyzed in this survey. The mean age of the first period was 45.4, and of the second 50.3 years old. The incidences of sarcoidosis (11.0%, 13.7%) and Vogt-Koyanagi-Harada disease (5.7%, 5.9%) were virtually unchanged in the two series. However, the incidence of Behçet's disease was higher in the first period (10.6%) than in the second (5.8%). The frequency of herpetic iritis (1.8%, 4.7%) and intraocular lymphoma (0.4%, 2.6%) showed apparent increase. Unclassified uveitis decreased from 55.6% to 47.5%.
Conclusions: The etiologies of uveitis have changed with the progress of diagnostic techniques and the establishment of new disease concepts.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 119: 678-685, 2015.

Key words
Uveitis, Multiplex polymerase chain reaction, Behçet's disease, Herpetic virus, Intraocular lymphoma
Reprint requests to
Masaru Miyanaga, M.D. Department of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University. 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8591, Japan