Purpose: To evaluate the effectiveness of selective laser trabeculoplasty (SLT) on steroid-induced glaucoma.
Methods: The study included 46 eyes of 41 subjects who were followed up for at least 12 months after SLT. The included 10 eyes with steroid-induced glaucoma, 16 eyes with primary open angle glaucoma (POAG), 10 eyes with pseudoexfoliation glaucoma (PEX.G) and 10 eyes with mixed glaucoma (Mixed.G). The range of the SLT laser was 360 degrees. Intraocular pressure (IOP) before and after SLT, and cumulative survival rate after SLT were determined.
Results: Significant decreases in IOP were observed after SLT in the steroid-induced glaucoma group, the POAG group and the PEX.G group. At 12 months after SLT, preoperation IOP decreased by 35.9% (29.9±7.5 mmHg to 17.9±2.2 mmHg) in the steroid-induced glaucoma group, 13.2% (20.0±3.0 mmHg to 17.3±3.1 mmHg) in the POAG group, 10.7% (21.1±4.0 mmHg to 18.1±4.1 mmHg) in the PEX.G group and 6.9% (21.3±1.9 mmHg to 19.9±3.4 mmHg) in the Mixed.G group. Cumulative survival rates were 80%, 56.3%, 50.0%, 40.0% in the steroid-induced glaucoma, POAG, PEX.G, and Mixed.G groups, respectively, at 12 months after SLT (Logrank test, p=0.467).
Conclusion: These data suggest that SLT increased IOP reduction rates for steroid-induced glaucoma more than for any other group.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 116: 751-757, 2012.