Abstract

Volume.117 Number.2

Original article : Clinical science

Association between Age and Chorioretinal Hemodynamics in Normal Volunteers Examined with Laser Speckle Flowgraphy
Akiko Tamura1, Akiko Kogure1, Goro Watanabe2, Shoji Kishi2, Sadao Hori1,3
1 Department of Ophthalmology, Tokyo Women's Medical University
2 Department of Ophthalmology, Gunma University School of Medicine
3 Nishikasai Inouye Eye Hospital

Purpose: To investigate the relationship between age and chorioretinal hemodynamics in normal volunteers examined with Laser speckle flowgraphy (LSFG-NAVI).
Subjects and Methods: 107 eyes of 107 healthy volunteers aged from 21 to 78 years old were included. Laser speckle flowgraphy measurements of relative blood velocity (mean blur rate: MBR), skewness in the wave of blood velocity (Skew) and blowout score (BOS), which indicates ease of blood flow, were obtained as parameters of chorioretinal hemodynamics. MBR and BOS were measured on the optic disc and macula, and BOS and Skew were measured in retinal arteries and veins.
Results: There was a negative correlation between age and MBR on the optic disc and macula. There was a negative correlation between age and BOS on the optic disc, macula, retinal arteries and retinal veins.
Conclusion: There was a negative correlation between MBR, BOS and age in all measurement areas. MBR and BOS may serve as indexes for a new interpretation of fundus pathology including age-related arterial sclerosis.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 117: 110-116, 2013.

Key words
Laser speckle flowgraphy (LSFG-NAVI), Age, Chorioretinal hemodynamics, Healthy volunteers
Reprint requests to
Akiko Tamura, M.D.　Department of Opthalmology, Tokyo Women's Medical University. 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan
Received: 18 November 2011. Accepted in revised form: 23 August 2012.
Nihon Ganka Gakkai Zasshi 117: 110-116,2013