Original article : Clinical science
Preference and Trends of Treatment for Diabetic Retinopathy in Korea and Japan
Miho Nozaki1, Kiyoshi Suzuma2, Makoto Inoue3, Ryo Kawasaki4, Teruyo Kida5, Yoshihiro Takamura6, Taiji Nagaoka7, Tomoaki Murakami8, Shigeo Yoshida9; Korea-Japan Diabetic Retinopathy Study Group
1 Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences
2 Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University
3 Kyorin Eye Center, Kyorin University School of Medicine
4 Department of Public Health, Yamagata University Faculty of Medicine
5 Department of Ophthalmology, Osaka Medical College
6 Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui
7 Department of Ophthalmology, Asahikawa Medical University
8 Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine
9 Department of Ophthalmology, Kyushu University Graduate School of Medical Sciences
Purpose: The difference in preferences and trends of treatment in each country are important to plan an international interventional clinical study in eastern Asia. Accordingly, we compared the preferences and trends in treatment of diabetic retinopathy in Korea and Japan.
Methods: We obtained answers to questionnaires (49 questions) from 91 ophthalmologists of the Korean Retina Society and 120 ophthalmologists of the Japanese Society of Ophthalmic Diabetology in June/July, 2012. Some of the questions were modified from The Preferences and Trends (PAT) survey of American Society of Retina Specialists.
Results: The first choice for a patient with vision of 20/25, clinically significant diabetic macular edema and clear evidence of intraretinal fluid on spectral domain OCT were intravitreal anti-vascular endothelial growth factor agent (31%) in Korea and sub-Tenon steroid (22%) in Japan. The management for a patient with refractory neovascular glaucoma who has closed angle and persistent intraocular pressure elevation (>50 mmHg) were glaucoma drainage implant surgery (74%) in Korea and trabeculectomy (57%) in Japan.
Conclusion: There were differences in preferences and trends of treatment for diabetic retinopathy between Korea and Japan. The differences need to be considered when planning international clinical studies.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 117: 735-742, 2013.
Key words
Diabetic Retinopathy, Preferences and Trends (PAT) survey, Korea, Japan, International interventional clinical study
Reprint requests to
Miho Nozaki, M.D. Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences. 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan
Received: 30 January 2013. Accepted in revised form: 12 April 2013.
Nihon Ganka Gakkai Zasshi
117: 735-742,2013
