Abstract

Volume.125 Number.5

Original article : Short report

A Case Report of Binocular Endogenous Fungal Endophthalmitis Associated with Complicated Pyelonephritis: Additional Report
Rei Ogawa1, Hideki Fukuoka1, Kenji Nagata1, Koichi Makimura2, Chie Sotozono1
1 Department of Ophthalmology, Kyoto Prefectural University of Medicine
2 Department of Medical Mycology, Teikyo University School of Medicine

Purpose: To identify the fungal strains causing fungal endophthalmitis in a vitreous body and urinary tract stone in our previously published study entitled "A case of binocular endogenous fungal endophthalmitis associated with complicated pyelonephritis: A case report" (Nihon Ganka Gakkai Zasshi, 2019) and verify that they are the identical clones.
Methods: Matrix assisted laser desorption/ionization-time-of-flight mass spectrometry, drug susceptibility testing, and genetic polymorphism analysis were performed on eye- and kidney-isolated and cultured pathogens.
Results: Both fungal strains were identified as Candida albicans based on the results of the three analyses. The characteristics tested were identical in both strains.
Conclusion: Both strains were identical clones.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 125: 553-555, 2021.

Key words
Matrix assisted laser desorption/ionization-time-of-flight mass spectrometry, Antifungal drug susceptibility test, Genetic polymorphism analysis, Candida species
Reprint requests to
Hideki Fukuoka, M. D., Ph. D. Department of Ophthalmology, Kyoto Prefectural University of Medicine. 465 Kajii-cho, Kamigyo-ku, Kyoto, 606-8566, Japan