Abstract

Volume.127 Number.4

Original article : Clinical science

Short-term Postoperative Results of iStent Versus iStent Inject W Implantation Combined with Phacoemulsification
Honami Okabe1, Kimi Endo1, Takahiro Usui1, Sayaka Wada1, Yuki Kisanuki1, Tomomi Tomoyori1, Kota Yokoyama1, Seiya Fukuoka2, Eiko Miura2
1 Department of Ophthalmology, Showa University Northern Yokohama Hospital
2 Department of Ophthalmology, Showa University East Hospital

Purpose: We compared the short-term postoperative outcomes of iStent (iStent group) vs. iStent inject W (inject group) combined with phacoemulsification performed at Showa University Northern Yokohama Hospital.
Subjects and methods: From January 2019 to June 2021, we evaluated 35 eyes that could be followed up for up to 3 months after receiving an iStent or iStent inject W implantation combined with phacoemulsification. We compared the intraocular pressure(IOP)reduction, glaucoma eye drop scores, refractive errors, and complications at 1 and 3 months after surgery between iStent and iStent inject W. We defined a postoperative IOP of 15 mmHg or more as high IOP and less than 15 mmHg as low IOP.
Results: In the iStent group, the percentage of IOP elevation was 0.9±16.6%(mean±standard deviation)at 1 month postoperatively, with no significant increase (p=0.9589). The percentage of IOP reduction was 4.7±18.7% at 3 months postoperatively, with no significant decrease (p=0.5879). The percentages of IOP reduction were 15.3±16.0% at 1 month postoperatively (p=0.0097) and 20.7±14.9% at 3 months postoperatively in the inject group, with a significant difference between before and after surgery (p=0.0007). When comparing the percentage of IOP reduction between the inject and iStent groups, a significant IOP reduction was found in the inject group at 1 month (p=0.0114) and 3 months(p=0.0211)postoperatively. In the inject group, IOP was reduced by 25.8±15.2% in the high IOP group and 11.8±9.5% in the low IOP group at 3 months postoperatively. A significant IOP reduction was observed in the high IOP group (p=0.0439).
Conclusions: The IOP was lower in the inject group than in the iStent group. In the inject group, a significant IOP reduction was observed in the high IOP group.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 127: 463-470, 2023.

Key words
Micro-invasive glaucoma surgery (MIGS), iStent, iStent inject W, Glaucoma, Glaucoma surgery
Reprint requests to
Honami Okabe, M. D. Department of Ophthalmology, Showa University Northern Yokohama Hospital. 35-1 Chigasakichuo, Tsuzuki-ku, Yokohama-shi 224-8503, Japan