Purpose: We compared the causative disease of endogenous endophthalmitis, causative organisms, and time between the onset and surgery to investigate the factors that could improve visual outcomes.
Subjects and methods: A retrospective study was conducted on 14 eyes of 13 patients who diagnosed with endogenous endophthalmitis from April 2013 to February 2022, based on the medical records of our department.
Results: The mean age of the patients was 76.2 (42-89) years. There were 7 male and 6 female patients, and 7,2, and 4 patients had bacterial, fungal, and unknown pathologies, respectively. Of the 14 eyes, 7 had confirmed pre- and postoperative visual acuity, but 2 only had confirmed postoperative visual acuity. Of the 7 eyes for which pre- and post-vitrectomy visual acuity could be compared, 4 and 3 eyes were added to the improved and unimproved groups, respectively. The organisms responsible for infecting four eyes in the improved group were methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible Staphylococcus aureus (MSSA), whereas the causative organisms for infecting the remaining two eyes were unknown. The organisms responsible for infecting three eyes in the unimproved group were Klebsiella pneumoniae and group G streptococcus, whereas the causative organism for infecting the remaining one eye was unknown.
Conclusions: Patients in poor general condition can develop endogenous endophthalmitis due to various reasons. Early therapeutic intervention in such patients may improve the visual outcome of endogenous endophthalmitis, depending on the causative organism.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 127: 667-671,2023.