Background: Papillomacular retinoschisis may occur in patients with advanced glaucoma.
Cases: In case 1, a 67-year-old woman was diagnosed with enlarged optic disc cupping in both eyes and papillomacular retinoschisis in the left eye. On initial exami nation, the best corrected visual acuity (BCVA), intraocular pressure (IOP), and central foveal thickness (CFT) were 1.0,13 mmHg, and 476 μm, respecti vely, in the left eye. The papillomacular retino schisis improved gradually after starting the eye drop of carbonic anhydrase inhibitor (CAI). The BCVA, IOP, and CFT were 1.2,16 mmHg, and 244 μm, respectively, in the left eye; at a visit 71 months after starting eye drops of CAI. In case 2, a 76-year-old man was diagnosed with enlarged optic disc cupping in both eyes, papillomacular retinoschisis, foveal outer layer hole, and retinal detachment in the left eye. On initial presentation, the BCVA, IOP, and CFT were 0.5,11 mmHg, and 786 μm, respectively, in the left eye. The papillomacular retinoschisis and foveal detachment improved gradually after starting the eye drop of CAI. The BCVA, IOP, and CFT were 0.2,15 mmHg, and 173 μm, respectively, in the left eye; at a visit 61 months after starting eye drops of CAI. In case 3, an 85-year-old man was diagnosed with enlarged optic nerve head cupping in both eyes and papillomacular retinoschisis in the right eye. On initial presentation, the BCVA, IOP, and CFT were 0.3,8 mmHg, and 484 μm, respectively, in the right eye. The papillomacular retinoschisis improved gradually after starting the eye drop of CAI. The BCVA, IOP, and CFT were 0.5 (n.c.), 6 mmHg, and 202 μm, respectively, in the right eye; at a visit 31 months after starting the eye drop of CAI.
Conclusion: Long-term treatment with eye drops of CAI may lead to gradual improvement of macular retinoschisis associated with glaucoma without causing recurrences.
Nippon Ganka Gakkai Zasshi (J Jpn Ophthalmol Soc) 128: 79-86, 2024.